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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d07e5ea1da6dcfdea095116df91fc24e3f9b85744e9e51b9c82842acd69b290' 
  AND token = '1CU8aesdLRL0Utq5Cd7ys28vYjGWlpCi7hbu9Aymha8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}