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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75507d1af8f1fd3dcb58f617147098683c467e1de8498a8b760baed3c9818ba0' 
  AND token = 'Cq8/teesXImu6OLPPlq9ezTLPK452BG8/FkZMntoa0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}