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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '918968426c0d9d60d36ea7e067d87a8146a015b02c44855891021322957c20a6' 
  AND token = 'VZ/JQALG75SHppZqp2qyLLmKCRPss77Wgd1xm/qMuQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}