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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c2ff5cc1420dd34b28708fe0beeeb3ff182a5c5513153df949a3fbcbc500fe3' 
  AND token = 'oWNRrsrJKk+MHvamX3DkmIxkdKDWF8ZnzfJ4cMzDImA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}