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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2e0098c3f45d34f9ab858fe560240f2bda19890115c3ae6c08d1a7dafcb270' 
  AND token = 'WpocQOOaLXwC7ddEbZUZCpRrL4YuswmdlMNynfR8MbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}