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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84a8658363debb8f7e8e69a301078fb558adbf3b1c93560af5f7a05c41090d13' 
  AND token = '1ATmzkxhHpXzfJvLgQFjU/8ajoNa8LT/++UanEYc6Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}