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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cf6cbdc476c6e08d6478edaa831144d0c173096de43da6bf018b42780f8dea6' 
  AND token = 'MxPFDBNzzqcQI8f6FP3nrKey8UF1imwFBadX/l4neo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}