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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d179fc0a06cc2d68174421d3ca00d1c08da1250e28c5308157ba1a2e53245b4' 
  AND token = 'Mh9vKq/xxRFCCgnqSsUS4Ms0opaLEkkOC84cLDg7mCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}