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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '052eecc411e1d4607880d8c0705d2a7e612409e7fed00e1ef440f3c549d4576f' 
  AND token = '81heeb15uapQSmwm1mDFvBxvd2pj15S7XR1YlTBZsYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}