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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0dff45e20ab584dc448b857282bd474c01424d81bdd2221a3873e228d34e573' 
  AND token = '48cegIQ/aEIaL05IqobqLi/8wfUSBfnvzVSOuJ8LokE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}