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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc3dc08d317130c77ba909e8553d6f52587ea3d360f0cc69210773c7f38563b9' 
  AND token = 'p8qe/O7h6a8I+AeC1VH1Y15g5gj3IXn2RksxIGHd8Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}