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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b287ba49799df152fcfa74a168893ca7243c6543552c2dc299340881dcaab4c' 
  AND token = 'wbcmCRopL8nyYyObbbJfu0QjmAGwxtPa/YSOH6L6wuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}