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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51f06366beffc76824459628c13a579316be057e7fc2caf2b08f5f84e63de4b' 
  AND token = 'oBbP0fXIVbTQPrft8LuMb+BtC0DYZjMR8SdDdNN9ask=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}