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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e5b631018738fc332fe7890a6bf811a08c2e0d50ed85ba9d439de547a707a3' 
  AND token = 'GnffSr1Puk3DnFosvv/VOZ8L43iKWr1RX7WNLAiDARQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}