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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed8a4e3dd6e4ef0c94f12076535ccf6efef85e1fabd72a328b7886509871d2f' 
  AND token = 'IlpeVGwUZV/9sTUPzfkNESPLPC94qPtfPoSB07etXWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}