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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdfd4c46da4fc5d0cfc6c0c5e30abea1a2a3fbe348bff7bed61c4d7af9df4391' 
  AND token = 'HHRqckvxggBBYmDH/KtLH6yc7rZ8ogG/qDl6uYPwRcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}