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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667c0229f8fecd03f543e3a6cec78816247207fd0d822a14c3d3d40281a7a7de' 
  AND token = '3rnKkw+6L7X2ngys0/ZunVukQOjTt31B0VsL1GJ7Sjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}