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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163700b1536414035950ce3392399daaa5b5be427d43ade97357134bfe7cce3c' 
  AND token = 'mHRBZL+7fv9Zo0XaUXseIxKwl2k7kRd3vK/JNcNH6lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}