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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8508f1ad374ab6791644b30ea48cd044e8ada6ab881ef2da1b8c8f391cea7a' 
  AND token = 'r05ix71j4h80BrqDdvELWetNRubhTXQ24GdRy3BIFOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}