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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11af0a21e3416c1ee0562a19e09a08db51704079fc607821f40c009b51593139' 
  AND token = 'J3DEYOpQ5CImhU+N8rIjd1aaBQk1IjbzlDKUR3RTIz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}