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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40a2bb5a064168e9286c7f73c7fae10eb7492661a2d00c686de067d565303ad' 
  AND token = 'tMYPVQUyRXBgsfEJu6NzhLyZtOCMxfZfJV1BsDf2CdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}