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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c351b7db92a0f66db6df1c98a39a9e47d0716644674d3a6375606420c89cef5a' 
  AND token = 'vOSa75fLJQpM0qCIAfftwi8wYdGvVrqdMPAn57+88JY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}