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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ddaf9e1c1b126e43fa3150b15f5770205e880225f23c449f5d6c827ffa4f7cc' 
  AND token = 'BRTnXsTTpt6mPRiK491UyPuPLmzTfsFp6SiA1tNXTi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}