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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe46f0a1ae694204e0234bf5c37d9999775d701913bad5d64d9e37107482fd5b' 
  AND token = 'AiNnifCP7agu15w2VsvFTDwxiPY1g/S/JYHTeNgd9EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}