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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed5453b28b62a2784c611e52467569e5aedc4c77b25d3984c3dba9f08af7e65' 
  AND token = 'gEIxoZ9A1fyzgKaeV0WMd9kB5YKDibGqGbQKD2zh99w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}