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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a5462c1fd87e0102bc44449541e65524c2a2e1ae70e11e75e49fb9c186f4b4a' 
  AND token = 'ZiZTHz8Skas9HX5nIfdNN0IMoXvtWQMxhtwnUaDJAXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}