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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54dc998069f61c31004c4c12428d9f05d9445ac201be227f23580200a8b5a0c3' 
  AND token = 'r09yXRSFTxmqim8RALC7iEykA7xFaKkfpFDVx3Ei5/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}