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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf81f2e65fd311de05eb7f282ebbb5f486308ff5894c4c88d92914375089853c' 
  AND token = 'LWTo/fZM1Wf07NU6ImiTf4LJ60LyKCIEchCj13iIRPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}