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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343544c67086308fb1d823e5d829f58dba0b2e56e92e3c8b1708c2d22ad21eea' 
  AND token = 'Skk6EpEHu/8ddyS1C4SarXczOQLpIMSoO8Sc+XVS1iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}