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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8882d02e481c5bf234a6850ba8016d40f2c34e84582e535c7268d6a5937402' 
  AND token = '5PY0ylaS+UKEVvDHc0C57AiRko6v7icZPFeZDUwVnRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}