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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50835ff56cfc41667649b748ae16a1b1a8cb73c78c0da1dd5290e8c594d2b851' 
  AND token = 'vcU7cWjZOEfaHMua7rPMcx2+CEFP5sPKBUw/mkjaTQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}