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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b52449185830728cb913c8880ec10452e145abc440343992e34b6c28094eae' 
  AND token = '+fUJH8UUkJv+DIIedSvHb78kddSvW/a5+UValPrRwBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}