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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c11074b3c2e93fe34da4103d69226d86b1e6c60423bf92b54b1be8b8fd6a293' 
  AND token = 'QIC6Lfd+KXSZnUZnELpeVGuUv1k7wd4infY6tRHWQmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}