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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a2a28819682dbe05f449abd897a3e2a241e9924c5ed44583a8f1f527f62e8e' 
  AND token = 'nmsFNglwgi+t/AZLcAHb7Egp68qR/S6JDyT6Orel1go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}