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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b7f9a435e86a368ca1135a0ac88e261084c788788108b12288f92bf9d0b2a6' 
  AND token = 'iGtdxSCVFLxqLtv8QKVOXg4WUGmYylJYXeYGCN3SQxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}