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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0dd0c922a52c7d0e4bd133b6db76bd2afbc4fc1bf7b4f71cde8e7c5fb72149' 
  AND token = 'fyqS0IYZ3qPeONtSqmT/xsu2FrdChAvaZL7yuBB42Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}