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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acdfdb11de98ca7d8e326c0ed1fcc6fa845165fb83c7bb0359646f172b96ce6a' 
  AND token = 'I9cM4A74e/fz7PRRbCoLaVve8SmTkyv0ztGuM4yS+sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}