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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '624e7822e69d26d2509d9268da2f48c9f661a49a235f47c111a9f6e1fbcd8d31' 
  AND token = 'GctUm2/LYNWInXRtVF1fhpm6diDQ/0V26s9q3HYD/X0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}