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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e9926e3a28999b28d7c3e85157e7148be7c780d1e212726d90935bb23263f9e' 
  AND token = 'ozR1JhhzZfeMKiSqnt6udNrp/UWAWcc297r30kDOupw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}