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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e28c325e3d896192a4c54bdf570733768ee4e7e298b3013891a6f1c023e8d5' 
  AND token = 'T6Kusfb+d6OJTlF6EiGwch/NJM3dmbAq5AzSPiDRYws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}