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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bc69d3c8bf9aab428b28747e04de2485164e4c5f2d544567ea2f08754de3adb' 
  AND token = 'UW2a9D2Fez5osfl/oa+qDNHJDut8yC8i38spct9NXR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}