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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bc540fa5d53364cd7f847d365d494201149436c1c1198f8046c93f8b948d524' 
  AND token = '6i5xORCMWHvvRdCqPimPjtourpE4MmNcVL13gu7n1+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}