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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1177d381c7e19ce6bffda69de988a602bdff4c94bdc1c8c394fc3e3c0858c8c7' 
  AND token = 'xf9C7VJNJaz/NYMQ8FEc+mQZbJXHfEe4DFMugsdIASA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}