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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2853e102fc353a86f5d784bda584c24bc71879a6a461d623ca43edd2c218a1f2' 
  AND token = 'XhIxpqDzDVPyFA2o17vovvATdVsM+xnZ7su9fkW8+Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}