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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3fee9457cfd838b8d546b089cd6d0b3d05423efe580154a3bb2df027dfa0b26' 
  AND token = 'FtsPv57yWe2xy+OMDJ+oz9UcHtHgJUQmU6Ufr6BPIcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}