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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8af0df78ff091dfb0eb34384adecbf3d1495228e14470f340762a4e58a8b77e6' 
  AND token = 'Q54kjNZ9a2+k/EDzwMvL1ks9XqjIKgsibe1JTgNh2w8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}