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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd191063f269a1a473b2be4fdaf4ac4fe33c2da1dd382092f80e9a2787d7028de' 
  AND token = 'kT4clapevcpoDF1CPW7fP2Dpfqe1OPrIKOMdhFmvyB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}