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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f613cdd69d716e78360d53da97ae1bf6815e2e04450143c0c39c9799ec7ccbfa' 
  AND token = 'N3uDz9F6gBbydg0Wn8wUKbCMV0b+hl/CE0Ic1uF9qZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}