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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd873760e752da95bcda9e05a649702fe599791fd58510748d67b58f09b73f28' 
  AND token = 'LuSrI49kFzTmC4AbM+o8IAXCCNOn/4x6G4Ag6rXCo7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}