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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1468a389f90cca1b8d7c374ef4119d47c11530a1c3fad68ffb8f244ed2397c0a' 
  AND token = 'xKRxELm4HOMzXkiPj9RVrcHQMMBD6RHrUOUDKp6uQ5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}